Package: fbar 0.6.0

fbar: An Extensible Approach to Flux Balance Analysis

A toolkit for Flux Balance Analysis and related metabolic modeling techniques. Functions are provided for: parsing models in tabular format, converting parsed metabolic models to input formats for common linear programming solvers, and evaluating and applying gene-protein-reaction mappings. In addition, there are wrappers to parse a model, select a solver, find the metabolic fluxes, and return the results applied to the original model. Compared to other packages in this field, this package puts a much heavier focus on providing reusable components that can be used in the design of new implementation of new techniques, in particular those that involve large parameter sweeps. For a background on the theory, see What is Flux Balance Analysis <doi:10.1038/nbt.1614>.

Authors:Max Conway [aut, cre]

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NEWS

# Install 'fbar' in R:
install.packages('fbar', repos = c('https://maxconway.r-universe.dev', 'https://cloud.r-project.org'))

Peer review:

Bug tracker:https://github.com/maxconway/fbar/issues

Datasets:
  • ecoli_core - A small E. coli model, created from a number of sources.
  • iJO1366 - A full size E. coli model.
  • nutrient_types - A subset of exchange reactions annotated to indicate typical availability

On CRAN:

5.53 score 9 stars 25 scripts 271 downloads 13 exports 31 dependencies

Last updated 4 years agofrom:6619facb92. Checks:OK: 7. Indexed: yes.

TargetResultDate
Doc / VignettesOKNov 11 2024
R-4.5-winOKNov 11 2024
R-4.5-linuxOKNov 11 2024
R-4.4-winOKNov 11 2024
R-4.4-macOKNov 11 2024
R-4.3-winOKNov 11 2024
R-4.3-macOKNov 11 2024

Exports:decompose_metabolitesexpanded_to_glpkexpanded_to_gurobiexpanded_to_reactiontblexpanded_to_ROIfind_flux_variability_dffind_fluxes_dfgene_associategene_evalget_BiGGreactiontbl_to_expandedreactiontbl_to_gurobirecompose_metabolites

Dependencies:assertthatbackportscheckmateclicpp11dplyrECOSolveRfansigenericsgluelatticelifecyclemagrittrMatrixpillarpkgconfigpurrrR6registryrlangROIROI.plugin.ecosslamstringistringrtibbletidyrtidyselectutf8vctrswithr

Introduction

Rendered fromIntroduction.Rmdusingknitr::rmarkdownon Nov 11 2024.

Last update: 2020-09-02
Started: 2015-07-19

Multi-Objective Optimization case study

Rendered fromMulti-Objective_Optimization_case_study.Rmdusingknitr::rmarkdownon Nov 11 2024.

Last update: 2018-11-18
Started: 2017-01-13

Tutorial

Rendered fromTutorial.Rmdusingknitr::rmarkdownon Nov 11 2024.

Last update: 2017-09-23
Started: 2017-01-12